Malaria and people

School-age children found to be least protected from malaria

Insecticide-treated mosquito nets (ITN) reduce the chances of developing life-threatening malaria in Africa. However, recent research shows that older children, between the age of five and 19 years are the least well protected by nets. 05/10/09

Monkey malaria species is potentially deadly in humans

Wellcome Trust-funded research has identified key features of an new form of malaria infection, confirming the potentially deadly nature of the disease. 10/09/09

Malaria study points the way forward for genetic studies of disease in Africa

A study of children with malaria in the Gambia has provided new insights into how to conduct genetic studies of common diseases in African populations. 26/05/09

'Window into the brain' reveals deadly secrets of malaria

Looking at the retina in the eyes of patients with cerebral malaria has provided scientists with a vital insight into why malaria infection in the brain is so deadly. 15/01/09

Malaria vaccine trials offer hope of tackling major killer

The Kenya Medical Research Institute (KEMRI)-Wellcome Trust Research Programme has been at the centre of a major study to evaluate the world's most clinically advanced malaria vaccine candidate. 10/12/08

Treating severe malaria with a suppository saves lives in rural areas

A cheap suppository could save the lives of many people who develop severe malaria in remote rural areas of Africa and Asia, according to research published online in the 'Lancet'. 08/12/08

Modified viruses bring malaria vaccine hope

Oxford scientists have harnessed the power of pox and common cold viruses to create a new kind of malaria vaccine, which has shown huge promise in animal studies. 07/08/08

Maternal malaria researcher wins prestigious international prize

Groundbreaking research into treating malaria infections in pregnant women has earned international recognition for Professor Francois Nosten, Director of the Wellcome Trust-funded Shoklo Malaria Research Unit (SMRU) in Thailand. 11/06/08

Molyneux in Malawi

Professor Malcolm Molyneux's reflections on the achievements of the research centre in Blantyre and the challenges that remain in Malawi. 02/06/08

Alpha-thalassaemia may help protect against severe malarial anaemia

Researchers have moved a step closer to understanding why an over-abundance of red blood cells appears to offer protection against severe malarial anaemia. 18/03/08

Malaria vaccine trials begin using 'chimpanzee virus'

Trials funded by the Wellcome Trust are underway for a new vaccine to combat the most deadly form of malaria. 01/02/08

Monkey malaria widespread in humans and potentially fatal

A potentially fatal species of malaria is being commonly misdiagnosed as a more benign form of the disease, thereby putting lives at risk. 15/01/08

Mal variants discovered

A gene providing protection against infectious diseases such as malaria and tuberculosis can also increase the risk of disease. 29/03/07

Malaria's long-term legacy

Researchers in Kenya have tracked the incidence of neurological symptoms in infants with malaria, and have found that early infections expose many children to brain damage. 29/03/07

G6PD deficiency protects against severe malaria

Glucose-6-phosphate dehydrogenase deficiency is found to be protective against severe, life-threatening malaria. 13/03/07

Safer method for large-scale malaria screening developed

Researchers have developed a new test for detecting the malaria parasite in human urine and saliva. 20/11/06

Eye-opening research provides important diagnostic tool for cerebral malaria

The eye can provide a very reliable way of diagnosing cerebral malaria, researchers in Malawi have shown. 06/11/06

Using albumin to help treat children with severe malaria

A relatively simple intervention - albumin infusion - could save the lives of hundreds of thousands of children with severe malaria. 15/09/06

Malaria treatment efficacy compromised in certain patients with HIV

A weakened immune response resulting from HIV infection can lead to trouble when it comes to treating malaria. 09/09/06

Fake malaria drug implicated in Burmese man's death

A 23-year old man in Burma with malaria died because the medicine he received was fake, according to a report published in PLoS Medicine. 12/06/06

Malaria parasite impairs key immune system cells

Patients with malaria may be susceptible to a wide range of other infections, and fail to respond to several vaccines, because the parasite impairs the action of dendritic cells. 16/04/06

Trials show artesunate is more effective than quinine

The largest clinical trial ever conducted into the treatment of severe malaria in adults has found that using artesunate, medication derived from a Chinese herb, reduced the number of deaths by more than a third when compared with quinine, the most popularly used treatment. 30/08/05

Malaria and sickle cell trait

The blood cell abnormality sickle cell trait protects against malaria because of its effect on the immune response. 31/05/05

'Prime-boost' vaccine success

A new malaria vaccine has generated complete and long-lasting protection against experimental malaria infection. 16/04/05

Immune response keeps malaria hanging around for longer

Models suggest how the malaria parasite evades the human immune system so successfully. 10/06/04

Placental malaria increases mother-to-child HIV transmission

Placental malaria infection during pregnancy significantly increases the risk of mother-to-child transmission of HIV, according to researchers at the Johns Hopkins Bloomberg School of Public Health. 06/11/03