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The parasite

The malaria parasite is one of our most pernicious enemies, evading the immune system and rapidly acquiring resistance to the drugs designed to kill it. Explore research into the parasite genes, which make it so deadly, and into the latest drugs designed to combat the parasite's threat.

Features

Image for Haemoglobin consumption: Eating to stop bursting
Why do malaria parasites consume so much more haemoglobin than they need? 16/05/03
Image for The malaria genome unveiled
Chris Newbold looks at the some of the key findings in the genome of the malaria parasite Plasmodium falciparum, and the implications for future research. 10/10/02
Image for The evolution of malaria parasites
Karen Day's studies are providing an insight into the close relationship between humans and malaria parasites over thousands of years. 09/10/02
Image for Developing Lapdap
The development of a new malaria therapy is a lengthy process. Professor Peter Winstanley discusses the story of Lapdap. 08/10/02
Image for Developing artemisinin
A yellowing, dog-eared copy of a Chinese research paper led the Wellcome Trust team in South-east Asia to the antimalarial drug artemisinin, now being used with great success in Thailand. 07/10/02
Image for The malaria medicine chest, part 1
With the rise of resistance in the malaria parasite, many antimalarial drugs are becoming useless. Nick White examines the current, perilous situation. 06/10/02
Image for The malaria medicine chest, part 2
Nick White examines the possibilities offered by artemisinin and combination therapy. 06/10/02
Image for Unravelling red cell rosetting
Alex Rowe is investigating why some forms of the malaria parasite cause red blood cells to clump together and form harmful 'rosettes'. 05/10/02
Image for Parasite functional genomics
An international team of researchers is using is using high-throughput techniques to understand what the genes in the Plasmodium falciparum genome actually do. 04/10/02
Image for Parasite comparative sequencing
The genome of Plasmodium falciparum is being compared to that of six other Plasmodium species at the the Wellcome Trust Sanger Institute's Pathogen Sequencing Unit. 03/10/02
Image for Modelling malaria virulence
The development of malaria vaccines is of crucial importance, but Andrew Read argues that their implementation needs to be handled carefully. 01/10/02
Image for The history of the Malaria Genome Project
How the international consortium came together. 01/10/02
Multidrug-resistant malaria is now prevalent in many parts of the world, with the highest rate of drug resistance in South-east Asia.
               
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